Postdoc (Senior Assistant ) in the group of researchers in the Laboratory of RNA Design and Therapeutics
University of Warsaw, Poland
Application deadline: 02 Aug 2026
This project applies deep learning to understand and predict RNA interactions with small molecules, a key challenge in RNA-targeted drug discovery. We will develop RNA language model-based methods for 3D structure prediction (OpenRNAFold) and extend the OpenRNADesign platform to generate RNA sequences and structures tailored to bind specific small molecules. Designed RNAs will be experimentally validated using SELEX and biochemical assays. The project combines computational innovation with wet-lab verification to advance the rational design of functional RNAs for therapeutic and biotechnological applications.
Key responsibilities include:
- Conducting SELEX experiments and biochemical assays for RNA aptamer selection and validation
- contributing to computational RNA design pipelines
- participating in data analysis
- manuscript preparation
- lab management.
Candidate profile:
- Ph.D. in molecular biology, biochemistry, or a related field. Required experience in RNA biochemistry and molecular biology techniques, including in vitro transcription, nucleic acid handling, and PCR/qPCR.
- They should also be able to take responsibility for day-to-day laboratory operations, including lab management, ordering and purchasing reagents, consumables, and other necessary materials, maintaining inventory, coordinating deliveries, organizing samples and documentation, ensuring that equipment and workspaces are properly maintained, and supporting the smooth functioning of experimental workflows in the lab.
- Optional expertise in aptamer selection methods, high-throughput sequencing library preparation, and/or analysis of sequencing datasets will be a strong advantage. Prior experience with biochemical/biophysical binding assays (e.g., MST, SPR, fluorescence anisotropy) will also be highly valued.
- The ideal candidate should have strong organizational skills, attention to detail, and the ability to work independently while collaborating effectively with computational scientists.
- The candidate should hold a PhD degree for no longer than 12 years before the date of signing an employment agreement in the project.
Deadline: 2 August 2026
For more information and to apply, please see here.
