What is this course about? The course aims to provide the theoretical background of popular biophysical methods that are often used in relation to Structural Biology research, and practical experience both in performing experiments and in analysing the resulting data. |
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Why should I attend? The rationale behind an extended kit of experiments to characterise macromolecules and their interactions will be explained. You will be shown how to perform and analyse the related experiments in dedicated practical sessions. The course is limited to 12 spaces. Therefore, please do not make any travel or other arrangements before being notified of your application outcome. |
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You can apply online for the event via this link. | ||||||
List of Lectures
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List of Practicals
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Organisers
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9:00 - 9:15 | Welcome and organisational issues, Anastassis Perrakis |
9:15 - 10:00 | Methods in Structural Audit, Patrick Celie |
| Cofee |
10:30 - 11:15 | Principles of ITC and kinetic applications, Philippe Dumas |
11:15 - 12:00 | Surface Plasmon Resonance, Alex Fish |
| Lunch |
13:00 - 15:30 | Practicals P1 / P2 / P3 |
| Coffee |
16:00 - 18:30 | Practicals P2 / P3 / P1 |
| Dinner at "Radeon" near NKI |
9:00 - 10:00 | Basics of fluorescence methods, Anastassis Perrakis & Alex Fish |
| Coffee |
10:30 - 11:15 | Haddock: modelling macromolecular interactions, Alexandre Bonvin |
11:15 - 12:00 | Microscale Thermophoresis, Katarzyna Walkiewicz |
| Lunch |
13:00 - 15:30 | Practicals P3 / P2 / P1 |
| Coffee |
16:00 - 18:30 | Practicals P4 / P5 / P6 |
| Free evening |
9:00 - 10:00 | Understanding enzymes by kinetics analysis, Kenneth Johnson |
| Coffee |
10:30 - 13:00 | Practicals P5 / P6 / P4 |
| Lunch |
13:45 - 14:30 | Advanced application of fluorescence methods, Peter Friedhoff |
14:30 - 17:00 | Practicals P6 / P4 / P5 |
| Coffee |
17:30 - 19:00 | Open Discussion on Experimental Strategy and Planning |
| Pizza Dinner at NKI |
20:00 - 21:00 | The Chemical Realm of Nature and the Nature of Chemistry, Nikos Psaros |
9:00 - 11:30 | Practical P7 (computational) |
11:30 - 13:00 | Global Fitting of kinetic data, Kenneth Johnson |
| Lunch |
13:30 - 16:00 | Practical P8 (computational) |
Departure |
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