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equipment available for NMR-based fragment screening:
AV III 600 MHz Cryo "Bud"
(equipped with helium-cooled 1H, 13C, 15N, 19F-QCI cryoprobe)
AV III HD 600 MHz Cryo "Bud" equipped with 19F-QCI probe and sample changer
We will acquire solution NMR spectra of user-provided samples and advise the user on the best NMR experimental setup to reach the specific research goals. For physical access, we will advise the user and provide NMR pulse programs as required. The facility is specialized for NMR fragment screening (typically recording 1H or 19F nuclei), including sample preparation from compound libraries.
Physical access: restricted
Remote access: restricted
Average time of a visit: 3 days
Sample preparation:
Biological NMR samples (proteins, RNA) as well as compound libraries need to be provided in a suitable form. Details will be advised by the BNMRZ scientific contacts before the visit.
BNMRZ (Bayerisches NMR-Zentrum)