We have applied some changes to ARIA and are monitoring stability, but you can continue to work as normal. We appreciate your understanding.
View All Crystallisation at Instruct
The NKI Protein Facility has a strong record in sample preparation for structural biology, and offers their users access to macromolecular crystallisation:
- Robotics for preparation of nanoliter crystallisation drops in 96-well format.
- Storage of crystallisation plates (4°C or 20°C).
- Screening and ranking of crystallisation conditions in 96-well format (TOPAZ, AutoInspex station).
Solving experimental (crystal, crye-EM) structures of macromolecjules and their complexes is beyond the scope of the NKI Protein facility access services for Instruct-ERIC!
The Facility has access to a high-throughput macromolecular crystallisation platform. Liquid handling robots are available for preparation of nanoliter crystallisation drops in 96-well format, including a 96-well pipetting robot (CyBi-SELMA) for filling up reservoir wells and a Mosquito for creating nanoliter crystallisation drops. Crystallisation trials can be stored and imaged by two RockImager systems, one at 4 °C and one at 20 °C. When suitable crystals are obtained for x-ray diffraction analysis, the applicant has to collaborate with a crystallography facility. Solving crystal structures is beyond the scope of the facility.
Plesmanlaan 121
1066 CX, Amsterdam
Netherlands
https://www.nki.nl/research/facilities-platforms/protein-facility
