A two-year post-doctoral position is available from September 2013 at the Department of Medical Biochemistry and Biophysics (MBB), Karolinska Institutet, Stockholm. The project deals primarily with over-expression, purification, crystallization and structure determination of human membrane proteins involved in the generation of lipid mediators of inflammation, belonging to the MAPEG (membrane associated proteins in eicosanoid and glutathione metabolism) superfamily. The successful candidate will join a multi-disciplinary research team and the position represents an opportunity for a postdoctoral scientist to develop his/her expertise as well as broaden his/her experience. The broad interests of the lab are in membrane protein structure and function. We will combine structural techniques such as macromolecular crystallography with biophysical and biochemical methods such as enzyme kinetics to investigate the structural bases of the catalytic mechanisms. The lab has all necessary equipment and access to facilities needed for the project. We have periodic access to beamlines at ESRF (France), Diamond (UK) and Bessy (Germany).
Qualifications:
The candidates should hold a Ph. D. degree, must be motivated and a have strong background in biochemistry or structural biology. Experience with protein expression, purification and biochemical characterisation is required. Prior experience in membrane protein biochemistry will be added advantages.
The application should contain a single PDF document including:
A Letter of intention stating the scientific interests, technical skills, and previous experience of the candidate.
C.V. including date and field of (expected) graduation and list of publications.
The contact information of at least two references.
Please send your electronic application to: Agnes.Rinaldo-Matthis@ki.se before 15th of June 2013.
