A 2-year postdoctoral position (with possibility for extension) is available in the research group of Dimphna meijer at TU Delf for a highly motivated individual interested in revealing molecular mechanisms of synapse assembly. Their research is focused on trans-synaptic interactions and downstream signalling during development of the central nervous system. These issues are addressed using a multidisciplinary approach that includes cryo-EM, cryo-ET, complemented with biochemical/biophysical techniques and mammalian cell biology.
The successful applicant will be the driver of a new project concerning detailed structural characterization of neuronal synapse assembly in a cellular context. State-of-the-art equipment, including high-end light and electron microscopes, as well as mammalian cell culture facilities are available in our department. With the support of technicians and experts in my research team, the postdoc will reconstitute a minimal synaptic junction to enable cryo-electron tomography of trans-synaptic complexes in a cellular setting. They are a young, international, growing team of multidisciplinary scientists. They aim for a high impact, supportive environment, where talented people work together to solve quantitative questions in neuroscience. See also their group website.
They are looking for a highly motivated and goal-oriented postdoctoral researcher with a Ph.D. degree in life sciences, structural biology, or related field. The ideal candidate has a background in structural biology. Experience with cryo-electron tomography, EM image analysis or neurobiology is a plus but not required. The candidate should be fluent in English and motivated to work in an ambitious and collaborative research team.
Interested candidates can apply by email by sending a cover letter, CV and the names of three references to: Dimphna Meijer Assistant Professor Delft University of Technology Kavli Institute of Nanoscience Delft Department of Bionanoscience Van der Maasweg 9, 2629 HZ Delft (Building 58) The Netherlands Email: d.h.m.meijer@tudelft.nl
