Post-doctoral position with i3S in Porto, Portugal
i3S - Instituto de Investigação e Inovação em Saúde/ Ipatimup - Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
Application deadline: 16 Feb 2023
A 12-month post-doctoral contract is available in Pedro Pereira’s group at i3S in Porto, Portugal, to work on the development of next-generation antithrombotic leads.
The successful candidate will specifically investigate the inhibition potency and anticoagulant activities in vitro of potential inhibitors screened by Random nonstandard Peptide Integrated Discovery (RaPID) and chemically synthesized in collaboration with Prof. Richard Payne (University of Sydney, Australia). The candidate will also study the molecular determinants of inhibition, using X-ray crystallography, perform SAR studies, and investigate the efficacy of lead compounds in vivo.
Applicant Requirements
- PhD degree in Biochemistry, Biology, Chemistry or a related scientific field. If a foreign higher education institution has conferred the degree, it must comply with the provisions of Decree-Law 66/2018, of 16th August, and any formalities established therein must be fulfilled by the date of signing the contract.
- Proven experience in Biochemistry, Structural Biology or a related discipline;
- Relevant publication track record (including first authorship of at least two peer- reviewed scientific publications) in international peer-reviewed journals, preferably in the fields mentioned above;
- Fluency in spoken and written English;
- Strong hands-on experience in molecular cloning, recombinant protein expression (E. coli and baculovirus systems) and purification, protein characterization, enzymology and macromolecular crystallography;
- Ability to work independently but also to be a proactive member within a multidisciplinary team.
Applications are open until February 16th 2023
Please contact Pedro Pereira for informal inquiries at ppereira@ibmc.up.pt.
