A post-doctoral position in protein crystallography and drug discovery is available in the Perry laboratory at the City of Hope Medical Center in Los Angeles, California. The project is focused on hits-to-leads studies against a novel diabetes therapeutic target for both type 1 and type 2 forms of the disease. This is a collaborative effort between three research groups at the City of Hope and is funded by a City of Hope grant for drug development.
The research will involve protein expression, purification, and protein crystallography studies to determine co-crystal structures of small molecule:protein target complexes, in addition to fragment-based drug discovery approaches. Biophysical methods including thermal shift assays and isothermal calorimetry will also be employed.
A PhD in biochemistry or related discipline with a strong background in protein crystallography is required.
Kindly send your cover letter and CV to me at: jperry@coh.org
