One PhD Position is available in the lab of Massimo Degano to use an integrated structural biology approach to study the role of B-cell receptors in different forms of leukaemia and lymphomas. Goal of the project is the characterization of the structure of BCRs from hematological malignancies using X-ray crystallography and cryoEM to guide the identification of compounds that can antagonize the pathogenic BCR-mediated signaling. Lead compounds will be validated in vitro, as well as in cellular models to assess their effect on proliferation.
All relevant information on how to apply and the selection process can be found at the website
The deadline for applications is July 10th 2023, 1:00 pm CEST (Rome time).