Krios manager position available at Northwestern University
United States
Application deadline: 29 May 2026
Northwestern University seeks to recruit an enthusiastic and motivated cryo-electron microscopy (cryo-EM) Facility Manager to join the Structural Biology Facility (SBF), located on the Evanston campus. The successful applicant will be responsible for managing a new Krios instrument and contributing to basic and translational research programs on both the Evanston and Chicago campuses. The SBF cryo-EM facility currently houses a TFS Glacios and JEOL 1400 TEM. In addition, a new TFS Krios G4 will be operational in September of 2025. The Krios is equipped with a Selectris energy filter and a Falcon 4i direct electron detector. Several instruments for sample preparation are also available as part of the SBF.
Primary Responsibilities:
- Train and assist users in cryo-EM sample preparation, screening, and data collection
- Provide guidance to users on sample preparation, data collection, and the use of current image processing programs
- Help with administration of the Krios related portion of SBF (scheduling, billing, report writing, grant writing)
- Promote the Krios, and SBF in general, and participate in hands-on, group teaching of EM methods
- Contribute to the development and implementation of new EM experimental methods and protocols
- Maintain instruments to ensure optimal performance and high-quality sample preparation and data acquisition at all times
- Prepare samples and collect EM data for users who request staff service
Minimum qualifications:
Masters or Ph.D. degree with three years of hands-on cryo-EM experience in an EM laboratory.
Preferred qualifications:
- Ph.D. degree in biochemistry, biology, chemistry, physics or related field
- Experience in the use of TFS and JEOL microscopes and sample preparation
- Experience with cryo-EM data collection software (SerialEM and/or EPU) and image processing software packages (Relion, CryoSPARC, etc.)
- Prior experience with different aspects of structural biology research, such as data collection, structure determination, model building, and refinement
- Excellent technical, teaching, and verbal and written communication skills
- Ability to work with others and as a team member
This position will report to the Facility Director. Salary commensurate with qualifications and experience. Northwestern University provides excellent and competitive benefits.
Please submit your CV and ask for 2-3 reference letters to be directly sent to molbiosci@northwestern.edu. For full consideration, please submit your application by May 29, 2026.
