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We are looking for a Head of Cryo- Electron Microscopy Platform to join the Crick and advance our ambitions in delivering state-of-the-art science that applies cryo-EM to problems from the molecular to cellular scale.
We are looking to appoint an individual who has strengths in both experimental and in advanced computational methods in Cryo-EM. The post-holder will work in collaboration with Crick scientists to advance applications of Cryo-EM to a wide range of science at the Crick and, in conjunction with the Director of Science Technology Platforms, establish a long-term strategy for advancing the Cryo-EM platform.
The Cryo-EM platform has excellent facilities with two Titan Krios 300kV instruments, one fitted with a Gatan energy filter and K2 detector plus Falcon 4i and the other with a Selectris energy filter and Falcon 4i. These microscopes are complemented by a Talos Arctica 200kV and a Glacios 200kV, both with Falcon 3 detectors, and two 120kV Spirit TEM microscopes. More recently, the platform has incorporated an Aquilos-2 cryo-FIB instrument into their cryo-ET pipeline. The Crick Institute has excellent High Performance Computing resources, dedicated high-speed data storage and CPU and GPU clusters.
In collaboration with the Cryo-EM Operations Lead, the Cryo-EM Facility Manager and Crick scientists, the successful applicant will be responsible for developing and implementing the strategic vision for the future direction of the platform. This includes identifying research priorities and evaluating and promoting new techniques and technologies.
This is a particularly exciting position that will play a central role in how we develop and apply Cryo-EM at the Crick and have high visibility in the cryo-EM community.
If you are an experienced Cryo-EM scientist with a strong record of high-impact research and deep practical expertise spanning all aspects of Cryo-EM, from biochemistry and sample optimisation through to data collection, image processing, and structure determination, we’d love to hear from you.
