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4 FDA approved drugs; 15+ clinical candidates; 400+ patents; 20 years of GNF history! For over 21 years, the Genomics Institute of the Novartis Research Foundation (GNF) has been doing cutting-edge innovative drug discovery for Novartis global research organization, the Novartis Institute for BioMedical Research (NIBR).
The GNF Structure Based Discovery group is seeking a highly motivated Investigator level cryo-Electron Microscopist with a passion for applying cryo-EM to small molecule and biotherapeutic drug discovery. The successful candidate will work closely with an interdisciplinary team of scientists and collaborate with the cryo-EM community of the Novartis Institute of Biomedical Research to enable innovative structure based drug design. The chosen applicant will play an integral role in defining the direction and science of cryo-EM at GNF.
Your responsibilities:
• Execute on projects within the internal cryo-EM facility at GNF, a Glacios microscope equipped with Falcon 3 and CetaD cameras, interacting closely with cryo-EM colleagues in the Novartis structural biology community to optimize data, extend technology and collect data on the Novartis Titan Krios.
• Work within a group of dedicated structural biologists and protein scientists on cryo-EM sample production and preparation to translate macromolecular samples into three dimensional structure.
• Initiate and lead cryo-EM structural studies of drug targets in relevant therapeutic areas.
• Define, implement and communicate the impact of structural biology results and strategies to cross-disciplinary project teams throughout GNF and Novartis.
More information about the post and how to apply please follow this link
