A 1-year Post-doc position is available starting from January 2024. The overall goal of the project is the investigation of the DNA replication mechanism in Mycobacterium tuberculosis (MTB) using integrated structural biology methods, including NMR spectroscopy, X-ray crystallography, and Cryo-EM.
In particular, they aim at revealing the structural organization, the dynamic properties and the molecular interactions of the smaller and flexible proteins involved in the DNA replicative helicase loading in MTB, using high resolution Nuclear Magnetic Resonance (NMR) as main investigation method.
Environment: The Department of Science and Technological Innovation of the University of Easter Piedmont, Alessandria, provides access to the Magnetic Resonance Platform PRISMA, which comprises four high-resolution NMR spectrometers for solution NMR (two 500 MHz and two 400 MHz) and one for solid state NMR (500 MHz), a fast field-cycling relaxometer (0-10 MHz) and a high-field tunable relaxometer (20-120 MHz).
Skills/Qualification:
They are looking for a highly motivated candidate with strong scientific background, independence, and who enjoy working in a team. PhD in Chemistry, Physics, Biochemistry, Biophysics, Structural Biology or closely related fields is required. Prior experience with NMR is a prerequisite, with specific expertise in biomolecular NMR (protein structure determination by NMR, characterization of protein dynamics and protein-protein interactions).
To apply please send to Daniela Lalli (daniela.lalli@uniupo.it):
a cover letter (explaining your background and motivation);
your CV and publication list or a copy of the results obtained during the Master's degree;
contact information of referees;
TAG: structural biology, solution NMR, protein structure and dynamics
TYPE OF POSITION offered: Post doctoral Contract
CLOSING DATE: 31/01/2024 17:00
CONTACT: daniela.lalli@uniupo.it
ORGANIZATION: University of Eastern Piedmont
LOCATION: Alessandria
COUNTRY: Italy
