Recent advances have pushed the boundaries of structural biology, enabling the in situ structure determination of large protein complexes within their native cellular environments. Cryo-electron tomography (cryo-ET) bridges the gap to the cellular mesoscale by providing structural information for organelles and entire cells.
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The Cell Symposium, taking place 3-5 November, will highlight recent breakthroughs in the structure determination of physiological important proteins and macromolecular complexes both from isolated samples and in a cellular context. Additionally, the symposium will address virus structures that were obtained using different techniques including cryo-electron microscopy, cryo-ET, X-ray crystallography, NMR, and computational approaches within the framework of integrative structural biology. It will also discuss the functional insights gained from these structures and methodological advances that enabled these studies. The hope is to bring together structural biologists from different disciplines and interested scientists to discuss exciting new findings and conceptual advances in this field.
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